Healthcare decisions can be overwhelming, especially when it comes to choosing the right hospital that balances quality with cost-efficiency. Multispecialty hospitals offer a wide range of services under one roof—from cardiology and orthopedics to neurology and oncology.
In this guide, we’ve compared the top 10 multispecialty hospitals in the U.S. based on reputation, available specialties, and most importantly—average treatment costs. This helps patients make informed decisions while maximizing their insurance coverage and minimizing out-of-pocket expenses.
✅ Why Focus on Multispecialty Hospitals?
Multispecialty hospitals:
- Offer comprehensive diagnostics & treatments
- Reduce patient transfer delays
- Often have insurance partnerships for bundled pricing
- Are ideal for patients needing cross-specialty care
📊 Top 10 Multispecialty Hospitals & Their Cost Comparison
| Hospital | Location | Specialties | Average Cost of Surgery | Avg. Daily Inpatient Cost |
|---|---|---|---|---|
| 1. Mayo Clinic | Rochester, MN | Cardiology, Neurology, Oncology | $45,000 – $150,000 | $5,000 – $9,000 |
| 2. Cleveland Clinic | Cleveland, OH | Cardiology, Urology, Ortho | $50,000 – $140,000 | $4,800 – $8,500 |
| 3. Johns Hopkins Hospital | Baltimore, MD | Neurology, Gastroenterology, Oncology | $60,000 – $130,000 | $6,000 – $10,000 |
| 4. Massachusetts General Hospital | Boston, MA | Endocrinology, Oncology, Psychiatry | $55,000 – $125,000 | $5,200 – $9,800 |
| 5. Cedars-Sinai Medical Center | Los Angeles, CA | Ortho, GI, Cardiology | $50,000 – $135,000 | $5,500 – $9,000 |
| 6. UCSF Medical Center | San Francisco, CA | Nephrology, Transplant, Women’s Health | $40,000 – $120,000 | $5,700 – $9,500 |
| 7. Stanford Health Care | Stanford, CA | Precision Medicine, Cancer, Neurology | $70,000 – $200,000 | $6,500 – $11,000 |
| 8. NYU Langone Health | New York, NY | Orthopedics, Cardiovascular, Diabetes | $48,000 – $110,000 | $5,000 – $8,200 |
| 9. Houston Methodist Hospital | Houston, TX | Transplant, Cardio, Oncology | $60,000 – $150,000 | $4,900 – $8,500 |
| 10. Mount Sinai Hospital | New York, NY | Psychiatry, Surgery, Cardiology | $50,000 – $130,000 | $5,300 – $9,200 |
💵 Common Treatment Cost Breakdown (Estimated Ranges)
| Treatment | Average Cost in Multispecialty Hospitals |
|---|---|
| Heart Bypass Surgery | $90,000 – $150,000 |
| Hip Replacement | $40,000 – $60,000 |
| Chemotherapy (per cycle) | $10,000 – $25,000 |
| Brain Surgery | $80,000 – $160,000 |
| Kidney Transplant | $250,000 – $400,000 |
| MRI Scan | $3,000 – $7,000 |
| ICU Stay (per day) | $4,500 – $9,000 |
📌 Key Factors That Affect Cost:
- Insurance coverage & network agreement
- Inpatient vs outpatient setting
- Location (urban hospitals cost more)
- Doctor/surgeon fees
- Post-op rehabilitation